Nigella sativa oil protected the hippocampus against Acetyl cholinesterase and oxidative dysfunctions-driven impaired working memory in rats
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Nigella sativa Oil Enhances the Spatial Working Memory Performance of Rats on a Radial Arm Maze
Nigella sativa, an established historical and religion-based remedy for a wide range of health problems, is a herbal medicine known to have antioxidant and neuroprotective effects. This present study investigated the effect of Nigella sativa oil (NSO) administration on the spatial memory performance (SMP) of male adult rats using eight-arm radial arm maze (RAM). Twelve Sprague Dawley rats (7-9 ...
متن کاملThe Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats
Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro – alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (PTZ) - induced repeated seizures.There were 4 experimental groups including: 1- control group; received saline, 2- PTZ group ; received saline and PTZ (50 mg/kg, i.p) , 3-PTZ- NS 200 and 4...
متن کاملThe Effects of Nigella Sativa Hydro-alcoholic Extract on Memory and Brain Tissues Oxidative Damage after Repeated Seizures in Rats
Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro – alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (PTZ) - induced repeated seizures.There were 4 experimental groups including: 1- control group; received saline, 2- PTZ group ; received saline and PTZ (50 mg/kg, i.p) , 3-PTZ- NS 200 and 4...
متن کاملProtective effect of Nigella sativa oil against thioacetamide-induced liver injury in rats
The aim of this study was to investigate the possible protective effect of Nigella sativa oil (NSO) and compared with the N-acetylcysteine (NAC), an antioxidant which is known to have liver protective effects, against thioacetamide (TAA)-induced liver injury. Accordingly, we aimed to investigate the toxicity of a hepatotoxic agent, thioacetamide, compared the NSO and NAC liver preventive effect...
متن کاملThe hepatoprotective activity of olive oil and Nigella sativa oil against CCl4 induced hepatotoxicity in male rats
BACKGROUND Liver disease is the major cause of serious health problem leading to morbidity and mortality worldwide and the problem has increased in search for hepatotherapeutic agents from plants. The present study was designed to compare the probable hepatoprotective activity of olive oil and N. sativa oil on CCl4 induced liver damage in male rats. METHODS Forty males of a new model of albin...
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ژورنال
عنوان ژورنال: Bulletin of Faculty of Pharmacy, Cairo University
سال: 2019
ISSN: 2090-9101
DOI: 10.21608/bfpc.2019.47261